|
|
H2O + Benzyloxycarbonyl-Leu + H+ <=> L-leucine + CO2 + benzyl_alcohol
|
3.5.1.64
Nalpha-benzyloxycarbonylleucine hydrolase
|
–
|
|
|
BRENDA:
BR19252
KEGG:
R02552
MetaCyc:
3.5.1.64-RXN
|
|
|
|
L-leucine <=> (3R)-beta-leucine
|
5.4.3.7
leucine 2,3-aminomutase
|
–
|
BM
|
|
BRENDA:
BR31;
BS1198
KEGG:
R01091
MetaCyc:
LEUCINE-23-AMINOMUTASE-RXN
|
|
|
|
L-leucine + NAD+ + H2O <=> H+ + NH3 + NADH + 4-methyl-2-oxopentanoate
|
1.4.1.1
alanine dehydrogenase
1.4.1.20
phenylalanine dehydrogenase
1.4.1.23
valine dehydrogenase (NAD+)
1.4.1.8
valine dehydrogenase (NADP+)
1.4.1.9
leucine dehydrogenase
|
–
–
–
–
–
|
K
|
|
BRENDA:
BR33798
KEGG:
R01088
MetaCyc:
LEUCINE-DEHYDROGENASE-RXN
SABIO-RK:
1350
|
|
|
|
L-leucine + acetyl-CoA <=> H+ + N-acetyl-L-leucine + CoA
|
2.3.1.66
leucine N-acetyltransferase
|
–
|
|
|
BRENDA:
BR44067
KEGG:
R01089
MetaCyc:
LEUCINE-N-ACETYLTRANSFERASE-RXN
|
|
|
|
L-leucine + 2-oxoglutarate <=> L-glutamate + 4-methyl-2-oxopentanoate
|
2.6.1.1
aspartate transaminase
2.6.1.2
alanine transaminase
2.6.1.39
2-aminoadipate transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.6
leucine transaminase
2.6.1.67
2-aminohexanoate transaminase
2.6.1.9
histidinol-phosphate transaminase
|
–
–
–
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR47691
KEGG:
R01090
MetaCyc:
BRANCHED-CHAINAMINOTRANSFERLEU-RXN
SABIO-RK:
1352
|
|
|
|
N3-fumarylcarboxyamido-L-2,3-diaminopropionic_acid + L-leucine + ATP <=> 3-{[(2E)-4-amino-4-oxobut-2-enoyl]amino}-L-alanyl-L-leucine + ADP + phosphate + H+
|
6.3.2.47
dapdiamide synthase
|
–
|
BMK
|
|
BRENDA:
BR51332
KEGG:
R10944
MetaCyc:
RXN-16293
|
|
|
|
Ala-Leu + H2O <=> L-alanine + L-leucine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.14
cytosol alanyl aminopeptidase
3.4.11.22
aminopeptidase I
3.4.11.23
PepB aminopeptidase
3.4.13.12
Met-Xaa dipeptidase
3.4.13.18
cytosol nonspecific dipeptidase
3.4.13.19
membrane dipeptidase
3.4.13.20
beta-Ala-His dipeptidase
3.4.24.54
mucrolysin
|
–
–
–
–
–
–
–
–
–
|
|
|
BRENDA:
BS14594
MetaCyc:
RXN0-6979
|
|
|
|
ATP + L-leucine + H2O <=> ADP + phosphate + L-leucine + H+
|
7.4.2.1
ABC-type polar-amino-acid transporter
7.4.2.2
ABC-type nonpolar-amino-acid transporter
|
–
–
|
|
|
BRENDA:
BS372462
MetaCyc:
ABC-35-RXN
|
|
|
|
L-leucine <=> D-Leu
|
5.1.1.1
alanine racemase
5.1.1.10
amino-acid racemase
5.1.1.21
isoleucine 2-epimerase
|
–
–
–
|
|
|
BRENDA:
BS409693
MetaCyc:
RXN-20895
|
|
|
|
L-leucine + 2-oxoglutarate + O2 <=> 4-hydroxy-L-leucine + succinate + CO2
|
1.14.11
1.14.11.45
L-isoleucine 4-hydroxylase
|
–
–
|
|
|
BRENDA:
BS430322
MetaCyc:
RXN-13636
|
|
|
|
jasmonic_acid + L-leucine + ATP <=> jasmonoyl-L-leucine + AMP + diphosphate + H+
|
6.3
6.3.2.52
jasmonoyl---L-amino acid ligase
6.3.2.z
|
–
–
–
|
M
|
|
BRENDA:
BS443076
MetaCyc:
RXN-10437;
RXN-10459
|
|
|
|
ATP + L-leucine + tRNALeu <=> AMP + diphosphate + L-leucyl-tRNALeu
|
6.1.1.4
leucine---tRNA ligase
|
–
|
BK
|
|
BRENDA:
BR55
KEGG:
R03657
SABIO-RK:
412
|
|
|
|
N-acetyl-L-leucine + H2O <=> L-leucine + acetate
|
3.4.13.5
Xaa-methyl-His dipeptidase
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
3.5.1.15
aspartoacylase
3.5.1.16
acetylornithine deacetylase
|
–
–
–
–
|
|
|
BRENDA:
BS116181
SABIO-RK:
8151
|
|
|
|
Gly-Leu + H2O <=> glycine + L-leucine
|
3.4.11.1
leucyl aminopeptidase
3.4.13.18
cytosol nonspecific dipeptidase
3.4.13.19
membrane dipeptidase
3.4.13.20
beta-Ala-His dipeptidase
3.4.13.5
Xaa-methyl-His dipeptidase
3.4.22.40
bleomycin hydrolase
3.4.24.54
mucrolysin
3.5.1.32
hippurate hydrolase
|
–
–
–
–
–
–
–
–
|
|
|
BRENDA:
BS116317
SABIO-RK:
15464
|
|
|
|
Leu-NH2 + H2O <=> L-leucine + NH3
|
3.4.11.1
leucyl aminopeptidase
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.17
tryptophanyl aminopeptidase
3.4.11.2
membrane alanyl aminopeptidase
3.4.11.20
aminopeptidase Ey
3.4.11.24
aminopeptidase S
3.4.22.6
chymopapain
3.5.1.101
L-proline amide hydrolase
3.5.1.13
aryl-acylamidase
3.5.1.3
omega-amidase
3.5.1.4
amidase
3.5.1.57
tryptophanamidase
|
–
–
–
–
–
–
–
–
–
–
–
–
|
|
|
BRENDA:
BS140273
SABIO-RK:
14141
|
|
|
|
L-Leu-4-nitroanilide + H2O <=> L-leucine + 4-nitroaniline
|
3.3.2.6
leukotriene-A4 hydrolase
3.4.11.1
leucyl aminopeptidase
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.13
clostridial aminopeptidase
3.4.11.14
cytosol alanyl aminopeptidase
3.4.11.15
aminopeptidase Y
3.4.11.2
membrane alanyl aminopeptidase
3.4.11.20
aminopeptidase Ey
3.4.11.22
aminopeptidase I
3.4.11.23
PepB aminopeptidase
3.4.11.24
aminopeptidase S
3.4.11.3
cystinyl aminopeptidase
3.4.11.5
prolyl aminopeptidase
3.4.11.6
aminopeptidase B
3.4.11.9
Xaa-Pro aminopeptidase
3.4.11.B3
3.4.11.B5
3.4.11.B6
3.4.11.B9
3.4.16.5
carboxypeptidase C
3.4.21.25
cucumisin
3.4.21.26
prolyl oligopeptidase
3.4.22.40
bleomycin hydrolase
3.4.23.4
chymosin
3.5.1.13
aryl-acylamidase
|
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
|
|
|
BRENDA:
BS140301
SABIO-RK:
14444;
7842
|
|
|
|
Leu-Gly + H2O <=> L-leucine + glycine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.14
cytosol alanyl aminopeptidase
3.4.11.17
tryptophanyl aminopeptidase
3.4.11.2
membrane alanyl aminopeptidase
3.4.11.20
aminopeptidase Ey
3.4.11.22
aminopeptidase I
3.4.11.23
PepB aminopeptidase
3.4.11.6
aminopeptidase B
3.4.13.18
cytosol nonspecific dipeptidase
3.4.13.19
membrane dipeptidase
3.4.13.5
Xaa-methyl-His dipeptidase
3.4.24.54
mucrolysin
|
–
–
–
–
–
–
–
–
–
–
–
–
–
|
|
|
BRENDA:
BS14595
SABIO-RK:
12759;
12830
|
|
|
|
Leu-Leu + H2O <=> L-leucine + L-leucine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.14
cytosol alanyl aminopeptidase
3.4.11.15
aminopeptidase Y
3.4.11.20
aminopeptidase Ey
3.4.11.22
aminopeptidase I
3.4.11.23
PepB aminopeptidase
3.4.13.17
non-stereospecific dipeptidase
3.4.13.18
cytosol nonspecific dipeptidase
3.4.13.19
membrane dipeptidase
3.4.13.20
beta-Ala-His dipeptidase
|
–
–
–
–
–
–
–
–
–
–
–
|
|
|
BRENDA:
BS14597
SABIO-RK:
15466;
8161
|
|
|
|
Tyr-Leu + H2O <=> L-tyrosine + L-leucine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.16
Xaa-Trp aminopeptidase
3.4.11.23
PepB aminopeptidase
3.4.13.19
membrane dipeptidase
3.4.19.1
acylaminoacyl-peptidase
3.4.24.54
mucrolysin
|
–
–
–
–
–
–
|
|
|
BRENDA:
BS17162
SABIO-RK:
10571
|
|
|
|
L-leucine + O2 + H2O <=> 4-methyl-2-oxopentanoate + NH3 + H2O2
|
1.4.3.14
L-lysine oxidase
1.4.3.2
L-amino-acid oxidase
|
–
–
|
|
|
BRENDA:
BS258992
SABIO-RK:
9943
|
|
|
|
pyruvate + L-leucine <=> L-alanine + 4-methyl-2-oxopentanoate
|
2.6.1.12
alanine---oxo-acid transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.51
serine---pyruvate transaminase
2.6.1.84
arginine---pyruvate transaminase
2.6.1.9
histidinol-phosphate transaminase
|
–
–
–
–
–
|
|
|
BRENDA:
BS353456
SABIO-RK:
9857
|
|
|
|
L-leucine + glyoxylate <=> 4-methyl-2-oxopentanoate + glycine
|
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.44
alanine---glyoxylate transaminase
2.6.1.60
aromatic-amino-acid---glyoxylate transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
–
–
–
|
|
|
BRENDA:
BS354033
SABIO-RK:
13950
|
|
|
|
L-Leu-7-amido-4-methylcoumarin + H2O <=> L-leucine + 7-amino-4-methylcoumarin
|
3.3.2.6
leukotriene-A4 hydrolase
3.4.11.1
leucyl aminopeptidase
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.14
cytosol alanyl aminopeptidase
3.4.11.15
aminopeptidase Y
3.4.11.18
methionyl aminopeptidase
3.4.11.2
membrane alanyl aminopeptidase
3.4.11.20
aminopeptidase Ey
3.4.11.22
aminopeptidase I
3.4.11.3
cystinyl aminopeptidase
3.4.11.4
tripeptide aminopeptidase
3.4.11.6
aminopeptidase B
3.4.11.7
glutamyl aminopeptidase
3.4.22.16
cathepsin H
|
–
–
–
–
–
–
–
–
–
–
–
–
–
–
|
|
|
BRENDA:
BS355555
SABIO-RK:
12396
|
|
|
|
L-leucine + 2-oxoisovalerate <=> 4-methyl-2-oxopentanoate + L-valine
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356503
SABIO-RK:
6836
|
|
|
|
L-methionine + 4-methyl-2-oxopentanoate <=> 4-methylsulfanyl-2-oxobutanoate + L-leucine
|
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.88
methionine transaminase
|
–
–
|
|
|
BRENDA:
BS356573
SABIO-RK:
12601
|
|
|
|
Asp-Leu + H2O <=> L-aspartate + L-leucine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.23
PepB aminopeptidase
3.4.13.21
dipeptidase E
3.4.19.5
beta-aspartyl-peptidase
3.5.1.18
succinyl-diaminopimelate desuccinylase
|
–
–
–
–
–
|
|
|
BRENDA:
BS358910
SABIO-RK:
13274
|
|
|
|
Cys-Leu + H2O <=> L-cysteine + L-leucine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.23
PepB aminopeptidase
|
–
–
|
|
|
BRENDA:
BS358915
SABIO-RK:
15395
|
|
|
|
Leu-Cys + H2O <=> L-leucine + L-cysteine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.23
PepB aminopeptidase
|
–
–
|
|
|
BRENDA:
BS358931
SABIO-RK:
15396
|
|
|
|
Leu-Leu-Leu + H2O <=> L-leucine + Leu-Leu
|
3.4.11.1
leucyl aminopeptidase
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.15
aminopeptidase Y
3.4.11.4
tripeptide aminopeptidase
|
–
–
–
–
|
|
|
BRENDA:
BS361397
SABIO-RK:
9933
|
|
|
|
Leu-Pro-Leu-Arg-PheNH2 + H2O <=> L-leucine + Pro-Leu-Arg-PheNH2
|
3.4.11.20
aminopeptidase Ey
|
–
|
|
|
BRENDA:
BS361464
SABIO-RK:
13647
|
|
|
|
His-Pro-Leu + H2O <=> His-Pro + L-leucine
|
3.4.14.11
Xaa-Pro dipeptidyl-peptidase
3.4.14.5
dipeptidyl-peptidase IV
|
–
–
|
|
|
BRENDA:
BS361571
SABIO-RK:
10991
|
|
|
|
beta-Asp-Leu + H2O <=> L-aspartate + L-leucine
|
3.4.19.5
beta-aspartyl-peptidase
|
–
|
|
|
BRENDA:
BS361788
SABIO-RK:
13244
|
|
|
|
Leu-Gly-Gly + H2O <=> L-leucine + Gly-Gly
|
3.4.11.1
leucyl aminopeptidase
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.13
clostridial aminopeptidase
3.4.11.17
tryptophanyl aminopeptidase
3.4.11.24
aminopeptidase S
3.4.11.4
tripeptide aminopeptidase
|
–
–
–
–
–
–
|
|
|
BRENDA:
BS36279;
BS64773
SABIO-RK:
10617
|
|
|
|
Leu-Pro + H2O <=> L-leucine + L-proline
|
3.4.11.9
Xaa-Pro aminopeptidase
3.4.13.9
Xaa-Pro dipeptidase
|
–
–
|
|
|
BRENDA:
BS36382
SABIO-RK:
11084;
11275
|
|
|
|
Arg-Leu + H2O <=> L-arginine + L-leucine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.6
aminopeptidase B
|
–
–
|
|
|
BRENDA:
BS364767
SABIO-RK:
15465
|
|
|
|
Leu-Met + H2O <=> L-leucine + L-methionine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.2
membrane alanyl aminopeptidase
3.4.11.23
PepB aminopeptidase
|
–
–
–
–
|
|
|
BRENDA:
BS364794
SABIO-RK:
8141
|
|
|
|
angiotensin_I + H2O <=> angiotensin(1-9) + L-leucine
|
3.4.17.1
carboxypeptidase A
3.4.17.23
angiotensin-converting enzyme 2
|
–
–
|
|
|
BRENDA:
BS36689
SABIO-RK:
13312
|
|
|
|
benzyloxycarbonyl-Gly-Gly-Leu + H2O <=> benzyloxycarbonyl-Gly-Gly + L-leucine
|
3.4.17.1
carboxypeptidase A
3.4.17.15
carboxypeptidase A2
|
–
–
|
|
|
BRENDA:
BS36697
SABIO-RK:
11623
|
|
|
|
ATP + L-glutamate + L-leucine <=> ADP + phosphate + 5-L-glutamyl-L-leucine
|
6.3.2.2
glutamate---cysteine ligase
|
–
|
|
|
BRENDA:
BS369120
SABIO-RK:
7210
|
|
|
|
L-leucine <=> Isovalerate
|
not assigned
|
–
|
K
|
|
KEGG:
R08411
|
|
|
|
L-leucine + 2 O2 + 2 NADPH + 2 H+ <=> (E/Z)-isovaleraldoxime + 3 H2O + 2 NADP+ + CO2
|
1.14.13
|
–
|
K
|
|
KEGG:
R08664
|
|
|
|
peptide_with_an_N-terminal_L-leucine + H2O <=> L-leucine + peptide
|
3.4.11.10
bacterial leucyl aminopeptidase
|
–
|
|
|
MetaCyc:
3.4.11.10-RXN
|
|
|
|
tRNALeu + L-leucine + ATP <=> L-leucyl-[tRNALeu] + diphosphate + AMP
|
6.1.1.4
leucine---tRNA ligase
|
–
|
M
|
|
MetaCyc:
LEUCINE--TRNA-LIGASE-RXN
|
|
|
|
L-leucine + H+ <=> L-leucine + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-14649
|
|
|
|
L-leucine + L-threonine + L-2,4-diaminobutanoate + 6-methyloctanoyl-CoA + ATP <=> polymyxin_A + H+ + AMP + diphosphate + CoA
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-15242
|
|
|
|
L-leucyl-arginomycin + H2O <=> L-leucine + arginomycin
|
3.4.13
|
–
|
M
|
|
MetaCyc:
RXN-15932
|
|
|
|
demethylarginomycin + L-leucine + ATP <=> L-leucyl-demethylarginomycin + ADP + phosphate + H+
|
6.3.2
|
–
|
M
|
|
MetaCyc:
RXN-15934
|
|
|
|
L-leucyl-blasticidin_S + H2O <=> L-leucine + blasticidin_S
|
3.4.13
|
–
|
M
|
|
MetaCyc:
RXN-15935
|
|
|
|
demethylblasticidin_S + L-leucine + ATP <=> L-leucyl-demethyl-blasticidin_S + ADP + phosphate + H+
|
6.3.2
|
–
|
M
|
|
MetaCyc:
RXN-15937
|
|
|
|
L-leucine + 2-oxoglutarate + O2 <=> 5-hydroxy-leucine + succinate + CO2
|
1.14.11
|
–
|
M
|
|
MetaCyc:
RXN-16488
|
|
|
|
R-Hmp-MeVal-Phe-MePhe-Pro-alle-MeVal-[acp] + ATP + L-leucine <=> R-Hmp-MeVal-Phe-MePhe-Pro-alle-MeVal-Leu-[acp] + AMP + diphosphate + H+
|
6.3.2
|
–
|
M
|
|
MetaCyc:
RXN-16644
|
|
|
|
proto-zwittermicin_A-L-alanyl-[PKS] + L-leucine + L-methionine + O2 + NADPH <=> proto-zwittermicin_A + pyruvoyl-L-leucyl-L-methionine + NADP+ + H2O + polyketide-[acp]
|
2.3.1
|
–
|
M
|
|
MetaCyc:
RXN-16941
|
|
|
|
N-acetyldemethylphosphinothricinyl-L-alanyl-[PhsB_non-ribosomal_peptide_synthase] + L-leucine + PhsC_non-ribosomal_peptide_synthase + ATP <=> N-acetyldemethylphosphinothricinyl-L-alanyl-L-leucyl-[PhsC_non-ribosomal_peptide_synthase] + AMP + diphosphate + PhsB_non-ribosomal_peptide_synthase + H+
|
2.3.1
|
–
|
M
|
|
MetaCyc:
RXN-17195
|
|
|
|
L-leucine + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (E/Z)-isovaleraldoxime + oxidized_[NADPH-hemoprotein_reductase] + CO2 + H2O
|
1.14.14.M43
|
–
|
|
|
MetaCyc:
RXN-20853
|
|
|
|
L-leucine + O2 + reduced_[NADPH-hemoprotein_reductase] <=> N-hydroxy-L-leucine + oxidized_[NADPH-hemoprotein_reductase] + H+ + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-20907
|
|
|
|
indole-3-acetic_acid + L-leucine + ATP <=> H+ + (indol-3-yl)acetyl-L-leucine + diphosphate + AMP
|
6.3
|
–
|
M
|
|
MetaCyc:
RXN-2945
|
|
|
|
(indol-3-yl)acetyl-L-leucine + H2O <=> indole-3-acetic_acid + L-leucine
|
3.5.1.M7
|
–
|
M
|
|
MetaCyc:
RXN-2982
|
|
|
|
D-phenylalanyl-[gramicidin-S_synthetase] + L-proline + L-valine + L-ornithine + L-leucine + ATP <=> D-phenylalanyl-L-prolyl-L-valyl-L-ornithyl-L-leucyl-[NRPS-pcp] + AMP + diphosphate + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-9677
|
|
|
|
L-leucine <=> L-leucine
|
not assigned
|
–
|
|
|
MetaCyc:
RXN66-447
|
|
|
|
Na+ + L-leucine <=> Na+ + L-leucine
|
not assigned
|
–
|
|
|
MetaCyc:
TRANS-RXN-126B
|
|
|
|
H+ + L-leucine <=> H+ + L-leucine
|
not assigned
|
–
|
|
|
MetaCyc:
TRANS-RXN0-270
|
|
|
|
GWTLNSAGYLLGPHAIDNHRSFHDKYGLA-NH2 + H2O <=> Gly-Trp-Thr + Leu-Asn-Ser + Ala-Gly + L-tyrosine + L-leucine + LGPHAIDNHRS + FHDKYG + Leu-Ala-NH2
|
3.4.24.29
aureolysin
|
–
|
|
|
BRENDA:
BS405397
|
|
|
|
Leu-Gly-Arg-Ser-Gly-Gly-Asp-Ile-Ile-Lys-Lys-Met-Gln-Thr-Leu + H2O <=> L-leucine + Gly-Arg-Ser-Gly-Gly-Asp-Ile-Ile-Lys-Lys-Met-Gln-Thr-Leu
|
3.4.11.1
leucyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418787
|
|
|
|
Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu + H2O <=> Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu + L-leucine
|
3.4.17.B4
3.4.17.B5
|
–
–
|
|
|
BRENDA:
BS420173
|
|
|
|
Leu-Ala-Pro + H2O <=> L-leucine + Ala-Pro
|
3.4.11.9
Xaa-Pro aminopeptidase
|
–
|
|
|
BRENDA:
BS36361
|
|
|
|
L-leucine + 3-Indole-2-oxopropanoate <=> 4-methyl-2-oxopentanoate + L-tryptophan
|
2.6.1.28
tryptophan---phenylpyruvate transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.99
L-tryptophan---pyruvate aminotransferase
|
–
–
–
|
|
|
BRENDA:
BS353561
|
|
|
|
Leu-Ile + H2O <=> L-leucine + L-isoleucine
|
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.23
PepB aminopeptidase
|
–
–
|
|
|
BRENDA:
BS64755
|
|
|
|
propionyl-CoA + L-leucine <=> CoA + propionyl-L-leucine
|
2.3.1.66
leucine N-acetyltransferase
|
–
|
|
|
BRENDA:
BS321181
|
|
|
|
benzyloxycarbonyl-Val-Leu + H2O <=> Nalpha-carbobenzoxy-Val + L-leucine
|
3.4.16.5
carboxypeptidase C
|
–
|
|
|
BRENDA:
BS361664
|
|
|
|
L-leucine + 4-hydroxyphenylpyruvate <=> 4-methyl-2-oxopentanoate + L-tyrosine
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356515
|
|
|
|
Leu-Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu + H2O <=> L-leucine + SIINFEKL
|
3.4.11.1
leucyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418792
|
|
|
|
Diprotin_B + H2O <=> Val-Pro + L-leucine
|
3.4.14.11
Xaa-Pro dipeptidyl-peptidase
|
–
|
|
|
BRENDA:
BS361577
|
|
|
|
L-leucine + a_2-oxo_carboxylate <=> 4-methylsulfanyl-2-oxobutanoate + an_aliphatic_L-amino_acid
|
2.6.1.88
methionine transaminase
|
–
|
|
|
BRENDA:
BS417159
|
|
|
|
Leu-Arg-Pro-Gly + H2O <=> L-leucine + Arg-Pro-Gly
|
3.4.11.1
leucyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418786
|
|
|
|
L-leucine + 4-methyl-2-oxopentanoate <=> 4-methyl-2-oxopentanoate + L-leucine
|
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.6
leucine transaminase
|
–
–
|
|
|
BRENDA:
BS356502
|
|
|
|
5-L-glutamyl-L-leucine <=> 5-oxoproline + L-leucine
|
4.3.2.9
gamma-glutamylcyclotransferase
|
–
|
|
|
BRENDA:
BS321720
|
|
|
|
Kemptide + H2O <=> L-leucine + Arg-Arg-Ala-Ser-Leu-Gly
|
3.4.11.15
aminopeptidase Y
|
–
|
|
|
BRENDA:
BS361393
|
|
|
|
hippuryl-His-Leu + H2O <=> hippuryl-L-His + L-leucine
|
3.4.17.3
lysine carboxypeptidase
|
–
|
|
|
BRENDA:
BS36773
|
|
|
|
L-Leu-7-amido-4-carbamoylmethylcoumarin + H2O <=> L-leucine + Pro-7-amido-4-carbamoylmethylcoumarin
|
3.4.11.9
Xaa-Pro aminopeptidase
|
–
|
|
|
BRENDA:
BS450168
|
|
|
|
L-Leu-7-amido-4-carbamoylmethylcoumarin + H2O <=> L-leucine + 7-amino-4-carbamoylmethylcoumarin
|
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.2
membrane alanyl aminopeptidase
|
–
–
|
|
|
BRENDA:
BS432034
|
|
|
|
Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu + H2O <=> Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His + L-leucine
|
3.4.17.B4
3.4.17.B5
|
–
–
|
|
|
BRENDA:
BS420172
|
|
|
|
8-azaadenosine_5''-triphosphate + L-leucine + tRNALeu <=> 8-azaadenosine_5''-monophosphate + diphosphate + L-leucyl-tRNALeu
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS117
|
|
|
|
3''-dATP + L-leucine + tRNALeu <=> 3''-dAMP + diphosphate + L-leucyl-tRNALeu
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS112
|
|
|
|
8-methylaminoadenosine_5''-triphosphate + L-leucine + tRNALeu <=> 8-methylaminoadenosine_5''-monophosphate + diphosphate + L-leucyl-tRNALeu
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS116
|
|
|
|
8-bromoadenosine_5''-triphosphate + L-leucine + tRNALeu <=> 8-bromoadenosine_5''-monophosphate + diphosphate + L-leucyl-tRNALeu
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS118
|
|
|
|
tubercidin_5''-triphosphate + L-leucine + tRNALeu <=> tubercidin_5''-phosphate + diphosphate + L-leucyl-tRNALeu
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS115
|
|
|
|
2''-dATP + L-leucine + tRNALeu <=> 2''-dAMP + diphosphate + L-leucyl-tRNALeu
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS111
|
|
|
|
L-Leu-D-Leu + H2O <=> L-leucine + D-Leu
|
3.4.13.17
non-stereospecific dipeptidase
3.4.13.19
membrane dipeptidase
|
–
–
|
|
|
BRENDA:
BS412279
|
|
|
|
N-Formyl-Met-Leu + H2O <=> N-formyl-L-methionine + L-leucine
|
3.4.19.1
acylaminoacyl-peptidase
3.4.19.7
N-formylmethionyl-peptidase
|
–
–
|
|
|
BRENDA:
BS15153
|
|
|
|
L-Leu-hydrazide + H2O <=> L-leucine + azide
|
3.4.11.1
leucyl aminopeptidase
|
–
|
|
|
BRENDA:
BS382141
|
|
|
|
benzyloxycarbonyl-Leu-Leu + H2O <=> Benzyloxycarbonyl-Leu + L-leucine
|
3.4.16.5
carboxypeptidase C
|
–
|
|
|
BRENDA:
BS37216
|
|
|
|
benzyloxycarbonyl-Pro-Leu + H2O <=> Benzyloxycarbonyl-Pro + L-leucine
|
3.4.16.5
carboxypeptidase C
|
–
|
|
|
BRENDA:
BS361668
|
|
|
|
benzyloxycarbonyl-Nle-Leu + H2O <=> benzyloxycarbonyl-Nle + L-leucine
|
3.4.16.5
carboxypeptidase C
|
–
|
|
|
BRENDA:
BS361670
|
|
|
|
benzyloxycarbonyl-Ser-Leu + H2O <=> N-[(benzyloxy)carbonyl]-L-serine + L-leucine
|
3.4.16.5
carboxypeptidase C
|
–
|
|
|
BRENDA:
BS361666
|
|
|
|
jasmonoyl-L-leucine + H2O <=> jasmonic_acid + L-leucine
|
3.5.1.127
jasmonoyl-L-amino acid hydrolase
|
–
|
|
|
BRENDA:
BS439634
|
|
|
|
9-(L-leucylamino)-5H-benzo[a]phenoxazin-5-iminium + H2O <=> oxidized_kresyl_violet + L-leucine
|
3.4.11.2
membrane alanyl aminopeptidase
|
–
|
|
|
BRENDA:
BS449390
|
|
|
|
furylacryloyl-Phe-Leu + H2O <=> 3-(2-furyl)acryloyl-L-Phe + L-leucine
|
3.4.16.5
carboxypeptidase C
3.4.17.1
carboxypeptidase A
|
–
–
|
|
|
BRENDA:
BS361693
|
|
|
|
LVVYPWTQRF + H2O <=> L-leucine + VVYPWTQRF
|
3.4.11.2
membrane alanyl aminopeptidase
|
–
|
|
|
BRENDA:
BS394402
|
|
|
|
L-His-L-Leu + H2O <=> L-histidine + L-leucine
|
3.4.11.1
leucyl aminopeptidase
|
–
|
|
|
BRENDA:
BS364792
|
|
|
|
LGGGL + H2O <=> L-leucine + GGGL
|
3.4.11.22
aminopeptidase I
|
–
|
|
|
BRENDA:
BS450223
|
|
|
|
LGGGGGL + H2O <=> L-leucine + GGGGGL
|
3.4.11.3
cystinyl aminopeptidase
|
–
|
|
|
BRENDA:
BS450222
|
|
|
|
LGGGGGGGGGL + H2O <=> L-leucine + GGGGGGGGGL
|
3.4.11.22
aminopeptidase I
|
–
|
|
|
BRENDA:
BS450221
|
|
|
|
LGGGGGGGGGGL + H2O <=> L-leucine + GGGGGGGGGGL
|
3.4.11.22
aminopeptidase I
|
–
|
|
|
BRENDA:
BS450220
|
|
|
|
N-carbamoyl-L-leucine + H2O <=> L-leucine + CO2 + NH3
|
3.5.1.87
N-carbamoyl-L-amino-acid hydrolase
|
–
|
|
|
BRENDA:
BS189999
|
|
|
|
L-leucine <=> Hydroxypyruvate + NH3
|
4.3.1.17
L-serine ammonia-lyase
|
–
|
|
|
BRENDA:
BS141649
|
|
|
|
L-leucine + H2O + 3-acetylpyridine-deamino-NAD+ <=> 4-methyl-2-oxopentanoate + NH3 + 3-acetylpyridine_hypoxanthine_nucleotide
|
1.4.1.9
leucine dehydrogenase
|
–
|
|
|
BRENDA:
BS232372
|
|
|
|
L-leucine + H2O + 3-acetylpyridine_adenine_dinucleotide <=> 4-methyl-2-oxopentanoate + NH3 + reduced_acetylpyridine_adenine_dinucleotide
|
1.4.1.9
leucine dehydrogenase
|
–
|
|
|
BRENDA:
BS232370
|
|
|
|
L-leucine + H2O + deamido-NAD+ <=> 4-methyl-2-oxopentanoate + NH3 + deamino-NADH
|
1.4.1.9
leucine dehydrogenase
|
–
|
|
|
BRENDA:
BS232371
|
|
|
|
L-leucine + H2O + thio-NAD+ <=> 4-methyl-2-oxopentanoate + NH3 + thio-NADH
|
1.4.1.9
leucine dehydrogenase
|
–
|
|
|
BRENDA:
BS232374
|
|
|
|
L-leucine + H2O + 3-pyridinealdehyde-NAD+ <=> 4-methyl-2-oxopentanoate + NH3 + 3-pyridinealdehyde-NAD+
|
1.4.1.9
leucine dehydrogenase
|
–
|
|
|
BRENDA:
BS232373
|
|
|
|
L-leucine + H2O + 2 cytochrome_b <=> 4-methyl-2-oxopentanoate + NH3 + 2 reduced_cytochrome_b
|
1.4.99.B3
|
–
|
|
|
BRENDA:
BS439673
|
|
|
|
His-Leu + H2O <=> L-histidine + L-leucine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.17
tryptophanyl aminopeptidase
3.4.11.23
PepB aminopeptidase
3.4.24.54
mucrolysin
|
–
–
–
–
|
|
|
BRENDA:
BS17164
|
|
|
|
L-leucine <=> Isoamylamine + CO2
|
4.1.1.14
valine decarboxylase
4.1.1.57
methionine decarboxylase
|
–
–
|
|
|
BRENDA:
BS1315
|
|
|
|
N-Methyl-L-leucine + O2 + H2O <=> formaldehyde + L-leucine + H2O2
|
1.5.3.1
sarcosine oxidase
|
–
|
|
|
BRENDA:
BS259321
|
|
|
|
N-(5''-phospho-4''-pyridoxyl)-L-leucine + H2O + O2 <=> pyridoxal_5''-phosphate + L-leucine + H2O2
|
1.4.3.5
pyridoxal 5'-phosphate synthase
|
–
|
|
|
BRENDA:
BS451626
|
|
|
|
5''-phospho-pyridoxyl-L-leucine + H2O + O2 <=> pyridoxal_5''-phosphate + L-leucine + H2O2
|
1.4.3.5
pyridoxal 5'-phosphate synthase
|
–
|
|
|
BRENDA:
BS259081
|
|
|
|
4-Phenylazobenzyloxycarbonyl-Pro-Leu + H2O <=> 4-Phenylazobenzyloxycarbonyl-Pro + L-leucine
|
3.4.16.2
lysosomal Pro-Xaa carboxypeptidase
|
–
|
|
|
BRENDA:
BS36668
|
|
|
|
Acetyl-Phe-Leu + H2O <=> N-acetyl-L-phenylalanine + L-leucine
|
3.4.16.5
carboxypeptidase C
|
–
|
|
|
BRENDA:
BS361703
|
|
|
|
Benzyloxycarbonyl-Ala-Leu + H2O <=> Benzyloxycarbonyl-Ala + L-leucine
|
3.4.16.5
carboxypeptidase C
3.4.17.B4
3.4.17.B5
3.4.22.33
fruit bromelain
|
–
–
–
–
|
|
|
BRENDA:
BS16124
|
|
|
|
Leu-Trp-Leu + H2O <=> L-leucine + Trp-Leu
|
3.4.11.16
Xaa-Trp aminopeptidase
|
–
|
|
|
BRENDA:
BS358899
|
|
|
|
Leu-Trp-Met-Arg + H2O <=> L-leucine + Trp-Met-Arg
|
3.4.11.16
Xaa-Trp aminopeptidase
|
–
|
|
|
BRENDA:
BS358900
|
|
|
|
Ile-Leu + H2O <=> L-isoleucine + L-leucine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.23
PepB aminopeptidase
|
–
–
|
|
|
BRENDA:
BS358924
|
|
|
|
L-Leu-L-Pro-Gly-Gly + H2O <=> L-leucine + Pro-Gly-Gly
|
3.4.11.9
Xaa-Pro aminopeptidase
|
–
|
|
|
BRENDA:
BS36393
|
|
|
|
Leu-Pro-Pro + H2O <=> L-leucine + Pro-Pro
|
3.4.11.9
Xaa-Pro aminopeptidase
|
–
|
|
|
BRENDA:
BS36362
|
|
|
|
Leu-Pro-Pro + H2O <=> L-leucine + L-Pro-L-Pro
|
3.4.11.9
Xaa-Pro aminopeptidase
|
–
|
|
|
BRENDA:
BS432035
|
|
|
|
Nalpha-benzoyl-L-Leu + H2O <=> benzoate + L-leucine
|
3.4.17.B1
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
–
|
|
|
BRENDA:
BS189747
|
|
|
|
Nalpha-benzoyl-L-Leu + H2O <=> phenol + CO2 + L-leucine
|
3.5.1.64
Nalpha-benzyloxycarbonylleucine hydrolase
|
–
|
|
|
BRENDA:
BS116360
|
|
|
|
L-leucine + 2-oxobutyrate <=> 4-methyl-2-oxopentanoate + L-valine
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS437638
|
|
|
|
L-valine + 2-oxoisovalerate <=> 2-oxoisovalerate + L-leucine
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS437657
|
|
|
|
Benzyloxycarbonyl-Phe-Leu + H2O <=> benzyloxycarbonyl-Phe + L-leucine
|
3.4.16.5
carboxypeptidase C
3.4.16.6
carboxypeptidase D
3.4.17.1
carboxypeptidase A
3.4.17.4
Gly-Xaa carboxypeptidase
3.4.17.B1
|
–
–
–
–
–
|
|
|
BRENDA:
BS36696
|
|
|
|
Leu-enkephalin + H2O <=> L-tyrosine + L-leucine
|
3.1.1.7
acetylcholinesterase
|
–
|
|
|
BRENDA:
BS83081
|
|
|
|
Leu-enkephalin + H2O <=> L-leucine + Enkephalin
|
3.4.11.16
Xaa-Trp aminopeptidase
3.4.11.2
membrane alanyl aminopeptidase
3.4.11.3
cystinyl aminopeptidase
|
–
–
–
|
|
|
BRENDA:
BS358901
|
|
|
|
Leu-2-naphthylamide + H2O <=> L-leucine + 2-Naphthylamine
|
3.3.2.6
leukotriene-A4 hydrolase
3.4.11.1
leucyl aminopeptidase
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.14
cytosol alanyl aminopeptidase
3.4.11.2
membrane alanyl aminopeptidase
3.4.11.22
aminopeptidase I
3.4.11.3
cystinyl aminopeptidase
3.4.11.5
prolyl aminopeptidase
3.4.11.6
aminopeptidase B
3.4.19.1
acylaminoacyl-peptidase
3.4.22.16
cathepsin H
3.5.1.13
aryl-acylamidase
|
–
–
–
–
–
–
–
–
–
–
–
–
|
|
|
BRENDA:
BS140297
|
|
|
|
Leu-2-naphthylamide + H2O <=> L-leucine + naphthylamine
|
3.4.11.14
cytosol alanyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418783
|
|
|
|
Leu-Ala-Pro-Tyr-Lys-amide + H2O <=> L-leucine + Ala-Pro-Tyr-Lys-amide
|
3.4.11.22
aminopeptidase I
|
–
|
|
|
BRENDA:
BS364806
|
|
|
|
2-oxosuccinamic_acid + L-leucine <=> L-asparagine + 4-methyl-2-oxopentanoate
|
2.6.1.14
asparagine---oxo-acid transaminase
2.6.1.9
histidinol-phosphate transaminase
|
–
–
|
|
|
BRENDA:
BS354186
|
|
|
|
FVNQHLCGSHLVEAL + H2O <=> FVNQHLCGSHLVE + Ala-Leu + L-leucine
|
3.4.16.5
carboxypeptidase C
|
–
|
|
|
BRENDA:
BS409422
|
|
|
|
N-benzyloxycarbonyl-Ala-Ala-Leu + H2O <=> Benzyloxycarbonyl-Ala-Ala + L-leucine
|
3.4.17.18
carboxypeptidase T
|
–
|
|
|
BRENDA:
BS361778
|
|
|
|
L-Fur-Leu + H2O <=> Furoic_acid + L-leucine
|
3.4.17.B1
|
–
|
|
|
BRENDA:
BS397582
|
|
|
|
kallidin + H2O <=> L-leucine + bradykinin
|
3.4.11.1
leucyl aminopeptidase
|
–
|
|
|
BRENDA:
BS364752
|
|
|
|
L-leucine + 3-methyl-2-oxopentanoate <=> 4-methyl-2-oxopentanoate + L-isoleucine
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356501
|
|
|
|
L-Leu-D-Ala + H2O <=> L-leucine + D-alanine
|
3.4.13.19
membrane dipeptidase
|
–
|
|
|
BRENDA:
BS412277
|
|
|
|
L-Leu-D-Glu + H2O <=> L-leucine + D-glutamate
|
3.4.13.19
membrane dipeptidase
|
–
|
|
|
BRENDA:
BS412278
|
|
|
|
L-Leu-D-Ser + H2O <=> L-leucine + D-serine
|
3.4.13.19
membrane dipeptidase
|
–
|
|
|
BRENDA:
BS412280
|
|
|
|
Leu-Tyr + H2O <=> L-leucine + L-tyrosine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.16
Xaa-Trp aminopeptidase
3.4.11.23
PepB aminopeptidase
3.4.22.6
chymopapain
3.4.24.54
mucrolysin
3.5.1.13
aryl-acylamidase
|
–
–
–
–
–
–
–
|
|
|
BRENDA:
BS17161
|
|
|
|
L-Leu-benzyl_ester + H2O <=> L-leucine + benzyl_alcohol
|
3.4.11.1
leucyl aminopeptidase
|
–
|
|
|
BRENDA:
BS73924
|
|
|
|
L-Leu-benzyl_ester + H2O <=> L-leucine + benzoate
|
3.1.1.43
alpha-amino-acid esterase
|
–
|
|
|
BRENDA:
BS401268
|
|
|
|
L-leucyl-tRNALeu + H2O <=> L-leucine + tRNA
|
3.1.1.29
aminoacyl-tRNA hydrolase
|
–
|
|
|
BRENDA:
BS362952
|
|
|
|
benzyloxycarbonyl-Phe-Tyr-Leu + H2O <=> Benzyloxycarbonyl-Phe-Tyr + L-leucine
|
3.4.16.5
carboxypeptidase C
3.4.16.6
carboxypeptidase D
|
–
–
|
|
|
BRENDA:
BS391465
|
|
|
|
hippuryl-Lys-Leu + H2O <=> Hippuryl-L-Lys + L-leucine
|
3.4.17.3
lysine carboxypeptidase
|
–
|
|
|
BRENDA:
BS36771
|
|
|
|
L-pyroglutamyl-Leu + H2O <=> 5-oxoproline + L-leucine
|
3.4.19.3
pyroglutamyl-peptidase I
|
–
|
|
|
BRENDA:
BS74118
|
|
|
|
Leu-7-amino-4-trilfluoromethylcoumarin + H2O <=> L-leucine + 7-amino-4-trifluoromethylcoumarin
|
3.4.11.1
leucyl aminopeptidase
|
–
|
|
|
BRENDA:
BS382136
|
|
|
|
Thr-Leu + H2O <=> L-threonine + L-leucine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.23
PepB aminopeptidase
3.4.13.18
cytosol nonspecific dipeptidase
|
–
–
–
|
|
|
BRENDA:
BS364790
|
|
|
|
Val-Leu + H2O <=> L-valine + L-leucine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.23
PepB aminopeptidase
|
–
–
|
|
|
BRENDA:
BS358925
|
|
|
|
Benzyloxycarbonyl-Gly-Leu + H2O <=> Benzyloxycarbonyl-Gly + L-leucine
|
3.4.16.5
carboxypeptidase C
3.4.17.1
carboxypeptidase A
3.4.17.19
carboxypeptidase Taq
3.4.17.4
Gly-Xaa carboxypeptidase
3.4.22.33
fruit bromelain
|
–
–
–
–
–
|
|
|
BRENDA:
BS15048
|
|
|
|
benzyloxycarbonyl-Glu-Leu + H2O <=> Benzyloxycarbonyl-Glu + L-leucine
|
3.4.16.5
carboxypeptidase C
|
–
|
|
|
BRENDA:
BS361669
|
|
|
|
Leu-Leu-Tyr + H2O <=> L-leucine + Leu-Tyr
|
3.4.11.20
aminopeptidase Ey
|
–
|
|
|
BRENDA:
BS382203
|
|
|
|
succinyl-Leu-Leu-Val-Tyr-7-amido-4-methylcoumarin + H2O <=> N-Succinyl-L-Leu + L-leucine + Val-Tyr_4-methylcoumarin_7-amide
|
3.4.21.92
endopeptidase Clp
|
–
|
|
|
BRENDA:
BS15823
|
|
|
|
L-kynurenine + 4-methyl-2-oxopentanoate <=> 4-(2-aminophenyl)-2,4-dioxobutanoate + L-leucine
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS377045
|
|
|
|
gamma-glutamyl-L-leucine + H2O <=> L-leucine + L-glutamate
|
3.4.19.13
glutathione gamma-glutamate hydrolase
|
–
|
|
|
BRENDA:
BS423538
|
|
|
|
Leu-Trp + H2O <=> L-leucine + L-tryptophan
|
3.4.11.1
leucyl aminopeptidase
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.16
Xaa-Trp aminopeptidase
3.4.11.17
tryptophanyl aminopeptidase
3.4.13.19
membrane dipeptidase
|
–
–
–
–
–
|
|
|
BRENDA:
BS64752
|
|
|
|
L-leucine-4-anisidide + H2O <=> L-leucine + 4-anisidine
|
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.22
aminopeptidase I
|
–
–
|
|
|
BRENDA:
BS364749
|
|
|
|
FVNQHLCGSHLVEALYLVCGERGFFYTPKA + H2O <=> FVNQHLCGSH + LVEA + L-leucine + L-tyrosine + LVCGERGF + FYTPKA
|
3.4.23.18
aspergillopepsin I
|
–
|
|
|
BRENDA:
BS384735
|
|
|
|
FVNQHLCGSHLVEALYLVCGERGFFYTPKA + H2O <=> L-phenylalanine + VNQH + LCGSH + L-leucine + L-valine + L-glutamate + L-alanine + L-leucine + L-tyrosine + LVCG + ERG + L-phenylalanine + L-phenylalanine + YTPKA
|
3.4.23.21
rhizopuspepsin
|
–
|
|
|
BRENDA:
BS384742
|
|
|
|
L-leucine + H2O + NAD+ <=> trimethylpyruvate + NH3 + NADH
|
1.4.1.20
phenylalanine dehydrogenase
|
–
|
|
|
BRENDA:
BS373598
|
|
|
|
L-leucine + H2O + NAD+ <=> 2-oxoisovalerate + NH3 + NADH + H+
|
1.4.1.2
glutamate dehydrogenase
|
–
|
|
|
BRENDA:
BS441519
|
|
|
|
L-leucine + H2O + NAD+ <=> 3-methyl-2-oxopentanoate + NH3 + NADH
|
1.4.1.20
phenylalanine dehydrogenase
|
–
|
|
|
BRENDA:
BS232340
|
|
|
|
L-leucine + pyruvate + NADH <=> N-[1-(R)-(Carboxy)ethyl]-(S)-Leu + NAD+
|
1.5.1.28
opine dehydrogenase
|
–
|
|
|
BRENDA:
BS73118
|
|
|
|
L-leucine + oxaloacetate <=> 4-methyl-2-oxopentanoate + L-asparagine
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356517
|
|
|
|
N-acetyl-L-leucine + H2O <=> methanol + CO2 + L-leucine
|
3.5.1.64
Nalpha-benzyloxycarbonylleucine hydrolase
|
–
|
|
|
BRENDA:
BS116359
|
|
|
|
Lys-Leu + H2O <=> L-lysine + L-leucine
|
3.4.11.15
aminopeptidase Y
|
–
|
|
|
BRENDA:
BS423806
|
|
|
|
angiotensin_I + H2O <=> des-Leu10_angiotensin_I + L-leucine
|
3.4.17.1
carboxypeptidase A
|
–
|
|
|
BRENDA:
BS394232
|
|
|
|
L-norvaline + 4-methyl-2-oxopentanoate <=> 2-Oxopentanoate + L-leucine
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356567
|
|
|
|
Z-YL-H + H2O <=> Benzyloxycarbonyl-Tyr + L-leucine
|
3.4.16.6
carboxypeptidase D
|
–
|
|
|
BRENDA:
BS431675
|
|
|
|
PMVELAGE + H2O <=> PMVE + L-leucine + AGE
|
3.4.23.24
candidapepsin
|
–
|
|
|
BRENDA:
BS412711
|
|
|
|
PMVELQGE + H2O <=> PMVE + L-leucine + QGE
|
3.4.23.24
candidapepsin
|
–
|
|
|
BRENDA:
BS412716
|
|
|
|
PMVELTGE + H2O <=> PMVE + L-leucine + Tyr-Gly-Glu
|
3.4.23.24
candidapepsin
|
–
|
|
|
BRENDA:
BS412718
|
|
|
|
PMVELWGE + H2O <=> PMVE + L-leucine + WGE
|
3.4.23.24
candidapepsin
|
–
|
|
|
BRENDA:
BS412720
|
|
|
|
L-2-aminobutanoate + 4-methyl-2-oxopentanoate <=> 2-oxobutyrate + L-leucine
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356549
|
|
|
|
L-allo-isoleucine + 4-methyl-2-oxopentanoate <=> 3-methyl-2-oxopentanoate + L-leucine
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356545
|
|
|
|
L-leucine + 2-oxobutyrate <=> 4-methyl-2-oxopentanoate + 2-aminobutanoate
|
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
–
|
|
|
BRENDA:
BS356511
|
|
|
|
L-leucine + 2-oxooctanoate <=> 4-methyl-2-oxopentanoate + 2-aminooctanoate
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356520
|
|
|
|
L-leucine + 2-oxoisovalerate <=> 4-methyl-2-oxopentanoate + DL-valine
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS380007
|
|
|
|
L-leucine + 2-Oxohexanoate <=> 4-methyl-2-oxopentanoate + 2-aminohexanoate
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356508
|
|
|
|
L-norleucine + 4-methyl-2-oxopentanoate <=> 2-Oxohexanoate + L-leucine
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356569
|
|
|
|
L-leucine + 2-Oxopentanoate <=> 4-methyl-2-oxopentanoate + 2-aminopentanoate
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356510
|
|
|
|
L-leucine + prephenate <=> 4-methyl-2-oxopentanoate + 1-(2-amino-2-carboxyethyl)-4-hydroxycyclohexa-2,5-diene-1-carboxylic_acid
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356516
|
|
|
|
4-[(E)-2-[4-cyano-5-(dicyanomethylidene)-2,2-dimethyl-2,5-dihydrofuran-3-yl]ethenyl]phenyl_L-leucinate + H2O <=> L-leucine + 4-[(E)-2-(4-aminophenyl)ethenyl-3-cyano-5,5-dimethylfuran-2(5H)-ylidene]propanedinitrile
|
3.4.11.1
leucyl aminopeptidase
|
–
|
|
|
BRENDA:
BS418314
|
|
|
|
L-leucine + H2O + NADP+ <=> 4-methyl-2-oxopentanoate + NH3 + NADPH + H+
|
1.4.1.9
leucine dehydrogenase
|
–
|
|
|
BRENDA:
BS453892
|
|
|
|
2-oxoisovalerate + NADPH + NH3 <=> L-leucine + NADP+ + H2O
|
1.4.1.2
glutamate dehydrogenase
|
–
|
|
|
BRENDA:
BS387207
|
|
|
|
Benzyloxycarbonyl-Gly-Pro-Leu + H2O <=> Benzyloxycarbonyl-Gly-Pro + L-leucine
|
3.4.21.26
prolyl oligopeptidase
3.4.21.B28
|
–
–
|
|
|
BRENDA:
BS365337
|
|
|
|
Xaa-Leu + H2O <=> an_L-amino_acid + L-leucine
|
3.4.11.23
PepB aminopeptidase
|
–
|
|
|
BRENDA:
BS358907
|
|
|
|
Pro-Leu + H2O <=> L-proline + L-leucine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.13
clostridial aminopeptidase
3.4.11.5
prolyl aminopeptidase
3.4.13.18
cytosol nonspecific dipeptidase
3.4.13.9
Xaa-Pro dipeptidase
|
–
–
–
–
–
|
|
|
BRENDA:
BS36296
|
|
|
|
Trp-Leu + H2O <=> L-tryptophan + L-leucine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.17
tryptophanyl aminopeptidase
3.4.11.23
PepB aminopeptidase
3.4.13.23
cysteinylglycine-S-conjugate dipeptidase
|
–
–
–
–
|
|
|
BRENDA:
BS364787
|
|
|
|
Leu-systemin + H2O <=> L-leucine + systemin
|
3.4.11.1
leucyl aminopeptidase
|
–
|
|
|
BRENDA:
BS382207
|
|
|
|
Glu-Leu + H2O <=> L-glutamate + L-leucine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.23
PepB aminopeptidase
|
–
–
|
|
|
BRENDA:
BS358911
|
|
|
|
Leu-Arg + H2O <=> L-leucine + L-arginine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.2
membrane alanyl aminopeptidase
3.4.13.18
cytosol nonspecific dipeptidase
|
–
–
–
–
|
|
|
BRENDA:
BS364799
|
|
|
|
L-Leucinhydrazide + H2O <=> L-leucine + hydrazine
|
3.4.11.1
leucyl aminopeptidase
|
–
|
|
|
BRENDA:
BS73920
|
|
|
|
L-leucine_anilide + H2O <=> L-leucine + aniline
|
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.22
aminopeptidase I
|
–
–
|
|
|
BRENDA:
BS364747
|
|
|
|
L-Leu-4-nitroanilide + H2O <=> L-leucine + 2-nitroaniline
|
3.4.11.10
bacterial leucyl aminopeptidase
|
–
|
|
|
BRENDA:
BS64746
|
|
|
|
L-Leu-OEt + H2O <=> L-leucine + ethanol
|
3.1.1.43
alpha-amino-acid esterase
3.4.11.10
bacterial leucyl aminopeptidase
|
–
–
|
|
|
BRENDA:
BS64531
|
|
|
|
D-Leu-Leu + H2O <=> D-Leu + L-leucine
|
3.4.13.17
non-stereospecific dipeptidase
|
–
|
|
|
BRENDA:
BS64887
|
|
|
|
dibenzyloxycarbonyl-Lys-Leu + H2O <=> dibenzyloxycarbonyl-Lys + L-leucine
|
3.4.17.4
Gly-Xaa carboxypeptidase
|
–
|
|
|
BRENDA:
BS73993
|
|
|
|
Leu-Leu-OMe + H2O <=> L-leucine + L-Leu-O-methyl_ester
|
3.4.11.15
aminopeptidase Y
|
–
|
|
|
BRENDA:
BS361402
|
|
|
|
L-leucine + L-arginine <=> L-tyrosine + glycine
|
3.1.1.7
acetylcholinesterase
|
–
|
|
|
BRENDA:
BS83083
|
|
|
|
GFL + H2O <=> Phe-Leu + Gly-Phe + glycine + L-leucine
|
3.4.24.27
thermolysin
|
–
|
|
|
BRENDA:
BS367299
|
|
|
|
Benzyloxycarbonyl-Gly-Pro-Leu-Gly-Pro + H2O <=> Benzyloxycarbonyl-Gly-Pro + L-leucine + glycine + L-proline
|
3.4.22.B60
3.4.22.B62
|
–
–
|
|
|
BRENDA:
BS418123
|
|
|
|
N-acetyl-Ala-Leu + H2O <=> N-acetyl-L-alanine + L-leucine
|
3.4.19.1
acylaminoacyl-peptidase
|
–
|
|
|
BRENDA:
BS74015
|
|
|
|
N-benzyloxycarbonyl-Pro-Leu + H2O <=> N-benzyloxycarbonyl-Pro + L-leucine
|
3.4.16.2
lysosomal Pro-Xaa carboxypeptidase
|
–
|
|
|
BRENDA:
BS36664
|
|
|
|
N-chloroacetyl-L-leucine + H2O <=> Chloroacetate + L-leucine
|
3.4.13.5
Xaa-methyl-His dipeptidase
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
3.5.1.15
aspartoacylase
|
–
–
–
|
|
|
BRENDA:
BS140329
|
|
|
|
t-butyloxycarbonyl-L-Leu + H2O <=> tert-butanol + CO2 + L-leucine
|
3.5.1.64
Nalpha-benzyloxycarbonylleucine hydrolase
|
–
|
|
|
BRENDA:
BS116362
|
|
|
|
DL-alpha-aminoisocapronitrile + H2O <=> L-leucine + NH3
|
3.5.5.1
nitrilase
|
–
|
|
|
BRENDA:
BS141160
|
|
|
|
N-formyl-DL-leucine + H2O <=> formate + L-leucine
|
3.5.1.31
formylmethionine deformylase
|
–
|
|
|
BRENDA:
BS259949
|
|
|
|
N-formyl-DL-leucine + H2O <=> L-leucine + CO2
|
3.5.1.87
N-carbamoyl-L-amino-acid hydrolase
|
–
|
|
|
BRENDA:
BS190008
|
|
|
|
N-Methyl-L-leucine + acceptor + H2O <=> L-leucine + formaldehyde + reduced_acceptor
|
1.5.8.3
sarcosine dehydrogenase
|
–
|
|
|
BRENDA:
BS259383
|
|
|
|
Asn-Leu + H2O <=> L-asparagine + L-leucine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.23
PepB aminopeptidase
|
–
–
|
|
|
BRENDA:
BS358916
|
|
|
|
N-phenylacetyl-alpha-leucine + H2O <=> L-leucine + phenylacetate
|
3.5.1.11
penicillin amidase
|
–
|
|
|
BRENDA:
BS450372
|
|
|
|
N-benzyloxycarbonyl-L-Pro-Leu + H2O <=> Benzyloxycarbonyl-Pro + L-leucine
|
3.4.16.2
lysosomal Pro-Xaa carboxypeptidase
|
–
|
|
|
BRENDA:
BS452922
|
|
|
|
Leu-His + H2O <=> L-leucine + L-histidine
|
3.4.11.23
PepB aminopeptidase
|
–
|
|
|
BRENDA:
BS358933
|
|
|
|
Leu-Xaa + H2O <=> L-leucine + an_L-amino_acid
|
3.4.11.23
PepB aminopeptidase
|
–
|
|
|
BRENDA:
BS358926
|
|
|
|
benzyloxycarbonyl-His-Leu + H2O <=> benzyloxycarbonyl-His + L-leucine
|
3.4.16.5
carboxypeptidase C
|
–
|
|
|
BRENDA:
BS361667
|
|
|
|
benzyloxycarbonyl-Ile-Leu + H2O <=> benzyloxycarbonyl-Ile + L-leucine
|
3.4.16.5
carboxypeptidase C
|
–
|
|
|
BRENDA:
BS361665
|
|
|
|
furylacryloyl-Ala-Leu + H2O <=> furylacryloyl-Ala + L-leucine
|
3.4.16.5
carboxypeptidase C
|
–
|
|
|
BRENDA:
BS361696
|
|
|
|
5-L-glutamyl-L-leucine + Gly-Gly <=> L-leucine + 5-L-glutamyl-Gly-Gly
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
|
|
BRENDA:
BS420120
|
|
|
|
Leu-Asn + H2O <=> L-leucine + L-asparagine
|
3.4.11.1
leucyl aminopeptidase
3.4.13.23
cysteinylglycine-S-conjugate dipeptidase
|
–
–
|
|
|
BRENDA:
BS364775
|
|
|
|
Leu-Leu-Ala + H2O <=> L-leucine + Leu-Ala
|
3.4.11.4
tripeptide aminopeptidase
|
–
|
|
|
BRENDA:
BS364819
|
|
|
|
acetyl-Gly-Leu + H2O <=> N-acetylglycine + L-leucine
|
3.4.19.1
acylaminoacyl-peptidase
|
–
|
|
|
BRENDA:
BS365083
|
|
|
|
benzyloxycarbonyl-Glu-methyl_ester + L-leucine <=> benzyloxycarbonyl-Glu-Leu + methanol
|
3.4.21.19
glutamyl endopeptidase
|
–
|
|
|
BRENDA:
BS365258
|
|
|
|
ATP + L-methionine + L-leucine <=> ADP + phosphate + Met-Leu
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS400221
|
|
|
|
ATP + L-leucine + L-isoleucine <=> ADP + phosphate + Leu-Ile
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS428295
|
|
|
|
2 ATP + 3 L-leucine <=> 2 ADP + 2 phosphate + Leu-Leu-Leu
|
6.3.2.B16
|
–
|
|
|
BRENDA:
BS429638
|
|
|
|
3 ATP + 4 L-leucine <=> 3 ADP + 3 phosphate + L-leucyl-L-leucyl-L-leucyl-L-leucine
|
6.3.2.B16
|
–
|
|
|
BRENDA:
BS429699
|
|
|
|
4 ATP + 5 L-leucine <=> 4 ADP + 4 phosphate + L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-leucine
|
6.3.2.B16
|
–
|
|
|
BRENDA:
BS429737
|
|
|
|
ATP + N3-fumaroyl-L-2,3-diaminopropanoic_acid + L-leucine <=> ADP + phosphate + N-[(2S)-3-[[(2E)-4-amino-4-oxobut-2-enoyl]amino]-2-methylpropanoyl]-L-leucine
|
6.3.2.B15
|
–
|
|
|
BRENDA:
BR51260
|
|
|
|
ATP + H2O + L-leucine-[L-leucine-binding_protein][side_1] <=> ADP + phosphate + L-leucine + [L-leucine-binding_protein][side_1]
|
7.4.2.2
ABC-type nonpolar-amino-acid transporter
|
–
|
|
|
BRENDA:
BS444236
|
|
|
|
2 ATP + L-valine + 2 L-leucine <=> 2 ADP + 2 phosphate + L-Val-L-Leu-L-Leu
|
6.3.2.B16
|
–
|
|
|
BRENDA:
BS429641
|
|
|
|
2 ATP + 2 L-valine + L-leucine <=> 2 ADP + 2 phosphate + L-Val-L-Val-L-Leu
|
6.3.2.B16
|
–
|
|
|
BRENDA:
BS429631
|
|
|
|
ATP + L-leucine + glycine <=> ADP + phosphate + Leu-Gly
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS408616
|
|
|
|
ATP + L-leucine + L-alanine <=> ADP + phosphate + L-leucyl-L-alanine
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS400217
|
|
|
|
ATP + 2 L-leucine <=> ADP + phosphate + Leu-Leu
|
6.3.2.B16
|
–
|
|
|
BRENDA:
BS429907
|
|
|
|
ATP + L-aspartate + L-leucine <=> ADP + phosphate + Asp-Leu
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS428272
|
|
|
|
ATP + L-leucine + an_aliphatic_L-amino_acid <=> ADP + phosphate + Leu-Ala
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS398778
|
|
|
|
ATP + L-phenylalanine + L-leucine <=> ADP + phosphate + Phe-Leu
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS428312
|
|
|
|
ATP + L-proline + L-leucine <=> ADP + phosphate + Pro-Leu
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS428331
|
|
|
|
ATP + L-tryptophan + L-leucine <=> ADP + phosphate + Trp-Leu
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS408711
|
|
|
|
ATP + L-leucine + L-serine <=> ADP + phosphate + Leu-Ser
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS408617
|
|
|
|
ATP + L-asparagine + L-leucine <=> ADP + phosphate + Asn-Leu
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS408459
|
|
|
|
ATP + L-glutamine + L-leucine <=> ADP + phosphate + Gln-Leu
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS408533
|
|
|
|
ATP + L-leucine + L-cysteine <=> ADP + phosphate + Leu-Cys
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS408615
|
|
|
|
ATP + L-leucine + L-threonine <=> ADP + phosphate + L-leucyl-L-threonine
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS408618
|
|
|
|
ATP + L-leucine + beta-Alanine <=> ADP + phosphate + beta-Ala-L-Leu
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
|
BRENDA:
BS428294
|
|
|
|
Met-Leu + H2O <=> L-methionine + L-leucine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.23
PepB aminopeptidase
3.4.13.12
Met-Xaa dipeptidase
3.4.13.18
cytosol nonspecific dipeptidase
3.4.13.19
membrane dipeptidase
|
–
–
–
–
–
|
|
|
BRENDA:
BS364789
|
|
|
|
L-leucine + 3-methylthio-2-oxobutanoate <=> 4-methyl-2-oxopentanoate + L-methionine
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS356512
|
|
|
|
2-aminobenzoyl-Phe-Arg-Leu + H2O <=> 2-aminobenzoyl-Phe-Arg + L-leucine
|
3.4.18.1
cathepsin X
|
–
|
|
|
BRENDA:
BS380941
|
|
|
|
4-nitrophenyl-L-leucine + H2O <=> 4-nitrophenol + L-leucine
|
3.4.11.24
aminopeptidase S
|
–
|
|
|
BRENDA:
BS381214
|
|
|
|
furylacryloyl-Arg-Leu + H2O <=> furylacryloyl-Arg + L-leucine
|
3.4.16.5
carboxypeptidase C
|
–
|
|
|
BRENDA:
BS381889
|
|
|
|
furylacryloyl-Lys-Leu + H2O <=> furylacryloyl-Lys + L-leucine
|
3.4.16.5
carboxypeptidase C
|
–
|
|
|
BRENDA:
BS381891
|
|
|
|
L-Leu-4-methylumbelliferyl + H2O <=> L-leucine + 4-Methylumbelliferone
|
3.4.11.20
aminopeptidase Ey
|
–
|
|
|
BRENDA:
BS382134
|
|
|
|
Leu-Gly-Tyr-Leu + H2O <=> L-leucine + glycine + L-tyrosine + L-leucine
|
3.4.11.1
leucyl aminopeptidase
|
–
|
|
|
BRENDA:
BS382202
|
|
|
|
N-lauroyl-L-leucine + H2O <=> laurate + L-leucine
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
|
–
|
|
|
BRENDA:
BS385305
|
|
|
|
L-Leu-L-Val + H2O <=> L-leucine + L-valine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.10
bacterial leucyl aminopeptidase
3.5.1.13
aryl-acylamidase
|
–
–
–
|
|
|
BRENDA:
BS140303
|
|
|
|
L-Leu-4-(phenylazo)phenylamide + H2O <=> L-leucine + 4-phenylazophenylamine
|
3.4.11.1
leucyl aminopeptidase
|
–
|
|
|
BRENDA:
BS392383
|
|
|
|
Ser-Leu + H2O <=> L-serine + L-leucine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.23
PepB aminopeptidase
|
–
–
|
|
|
BRENDA:
BS358923
|
|
|
|
Leu-Ser + H2O <=> L-leucine + L-serine
|
3.4.11.1
leucyl aminopeptidase
3.4.13.18
cytosol nonspecific dipeptidase
|
–
–
|
|
|
BRENDA:
BS364795
|
|
|
|
N-hippuryl-His-Leu + H2O <=> hippuric_acid + L-histidine + L-leucine
|
3.4.15.1
peptidyl-dipeptidase A
|
–
|
|
|
BRENDA:
BS364948
|
|
|
|
ATP + L-leucine + tRNAMet <=> AMP + L-leucyl-tRNALeu + diphosphate
|
6.1.1.4
leucine---tRNA ligase
6.1.1.6
lysine---tRNA ligase
|
–
–
|
|
|
BRENDA:
BS368910
|
|
|
|
ATP + L-leucine + tRNALeu_from_Aquifex_aeolicus <=> AMP + diphosphate + L-leucyl-tRNALeu
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS453693
|
|
|
|
ATP + L-leucine + tRNALeu_from_Escherichia_coli <=> AMP + diphosphate + L-leucyl-tRNALeu
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS453694
|
|
|
|
ATP + L-leucine + tRNALeuA73 <=> AMP + diphosphate + L-leucyl-tRNALeu
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS368898
|
|
|
|
ATP + L-leucine + tRNALeuU73 <=> AMP + diphosphate + L-leucyl-tRNALeu
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS368899
|
|
|
|
ATP + L-leucine + tRNASer_mutant <=> AMP + diphosphate + L-leucyl-tRNALeu
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS368900
|
|
|
|
ATP + L-leucine + tRNALeu(UAG) <=> AMP + diphosphate + L-leucyl-tRNALeu
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS428300
|
|
|
|
ATP + L-leucine + tRNALeu(GAG) <=> AMP + diphosphate + L-leucyl-tRNALeu(GAG)
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS379405
|
|
|
|
ATP + L-leucine + tRNALeu(UAA) <=> AMP + diphosphate + L-leucyl-tRNALeu(UAA)
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS379406
|
|
|
|
ATP + L-leucine + tRNALeu(UUR) <=> AMP + diphosphate + L-leucyl-tRNALeu(UUR)
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS379407
|
|
|
|
ATP + L-leucine + tRNALeuA35G <=> AMP + diphosphate + L-leucyl-tRNALeuA35G
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS379408
|
|
|
|
ATP + L-leucine + tRNALeuA73G <=> AMP + diphosphate + L-leucyl-tRNALeuA73G
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS379409
|
|
|
|
AMP + diphosphate + L-leucyl-Pyrococcus_horikoshii_tRNALeu(GAG) <=> ATP + L-leucine + Pyrococcus_horikoshii_tRNALeu(GAG)
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS428163
|
|
|
|
ATP + L-leucine + Natrialba_magadii_tRNALeu(CAA) <=> AMP + diphosphate + L-leucyl-Natrialba_magadii_tRNALeu(CAA)
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS428297
|
|
|
|
ATP + L-leucine + Natrialba_magadii_tRNALeu(GAG) <=> AMP + diphosphate + L-leucyl-Natrialba_magadii_tRNALeu(GAG)
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS428298
|
|
|
|
ATP + L-leucine + [CmaA-protein-T-domain]-4''-phosphopantetheine <=> AMP + diphosphate + S-L-leucyl-[CmaA-protein-T-domain]-4''-phosphopantetheine
|
6.2.1.46
L-allo-isoleucine---holo-[CmaA peptidyl-carrier protein] ligase
|
–
|
|
|
BRENDA:
BS429940
|
|
|
|
ATP + L-leucine + tRNAUAALeu <=> AMP + diphosphate + L-leucyl-tRNACAALeu
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS443159
|
|
|
|
ATP + L-leucine + tRNACAGLeu <=> AMP + diphosphate + L-leucyl-tRNACAGLeu
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS443156
|
|
|
|
ATP + L-leucine + tRNAGAGLeu <=> AMP + diphosphate + L-leucyl-tRNAGAGLeu
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS443157
|
|
|
|
ATP + L-leucine + tRNAMet <=> AMP + diphosphate + L-leucyl-tRNAPhe
|
6.1.1.20
phenylalanine---tRNA ligase
|
–
|
|
|
BRENDA:
BS443158
|
|
|
|
ATP + L-leucine + tRNAUAALeu <=> AMP + diphosphate + L-leucyl-tRNAUAALeu
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS443160
|
|
|
|
ATP + L-leucine + tRNACAALeu <=> AMP + diphosphate + L-leucyl-tRNAUAALeu
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS443155
|
|
|
|
ATP + L-leucine + tRNALeuCUN <=> AMP + diphosphate + L-leucyl-tRNALeuCUN
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS453691
|
|
|
|
ATP + L-leucine + tRNALeuGAG <=> AMP + diphosphate + L-leucyl-tRNALeuGAG
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS453690
|
|
|
|
ATP + L-leucine + tRNALeuUUR <=> AMP + diphosphate + L-leucyl-tRNALeuUUR
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS453692
|
|
|
|
AMP-PNP + L-leucine + tRNALeu <=> AMP + Imidodiphosphate + L-leucyl-tRNALeu
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS113
|
|
|
|
Adenosine_5''-O-(3-thio)triphosphate + L-leucine + tRNALeu <=> adenosine_5''-monophosphate + thiodiphosphate + L-leucyl-tRNALeu
|
6.1.1.4
leucine---tRNA ligase
|
–
|
|
|
BRENDA:
BS114
|
|
|
|
L-Leu-L-Asp + H2O <=> L-leucine + L-aspartate
|
3.4.11.1
leucyl aminopeptidase
3.4.13.19
membrane dipeptidase
|
–
–
|
|
|
BRENDA:
BS364779
|
|
|
|
L-aspartate + 4-methyl-2-oxopentanoate <=> oxaloacetate + L-leucine
|
2.6.1.1
aspartate transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.6
leucine transaminase
|
–
–
–
|
|
|
BRENDA:
BS356317
|
|
|
|
N-phenylacetyl-Leu + H2O <=> phenylacetate + L-leucine
|
3.5.1.11
penicillin amidase
|
–
|
|
|
BRENDA:
BS367815
|
|
|
|
L-Leu-O-methyl_ester + H2O <=> L-leucine + methanol
|
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.24
aminopeptidase S
|
–
–
|
|
|
BRENDA:
BS382139
|
|
|
|
5-L-glutamyl-4-nitroanilide + L-leucine <=> 4-nitroaniline + 5-L-glutamyl-L-leucine
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
|
|
BRENDA:
BS321657
|
|
|
|
Leu-enkephalin-L-Tyr-Gly + H2O <=> L-leucine + enkephalin-L-Tyr-Gly
|
3.4.11.2
membrane alanyl aminopeptidase
|
–
|
|
|
BRENDA:
BS405711
|
|
|
|
L-leucine + L-methionine <=> Substance_P
|
3.1.1.7
acetylcholinesterase
|
–
|
|
|
BRENDA:
BS83085
|
|
|
|
L-glutamine + L-leucine <=> gamma-glutamyl-L-leucine + NH3
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
|
|
BRENDA:
BS455839
|
|
|
|
Gln-Leu + H2O <=> L-glutamine + L-leucine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.23
PepB aminopeptidase
|
–
–
|
|
|
BRENDA:
BS358917
|
|
|
|
L-glutamine + 4-methyl-2-oxopentanoate <=> 2-Oxoglutaramate + L-leucine
|
2.6.1.64
glutamine---phenylpyruvate transaminase
|
–
|
|
|
BRENDA:
BS356777
|
|
|
|
Leu-Ala + H2O <=> L-leucine + L-alanine
|
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.14
cytosol alanyl aminopeptidase
3.4.11.17
tryptophanyl aminopeptidase
3.4.11.2
membrane alanyl aminopeptidase
3.4.11.20
aminopeptidase Ey
3.4.11.22
aminopeptidase I
3.4.13.12
Met-Xaa dipeptidase
3.4.13.23
cysteinylglycine-S-conjugate dipeptidase
3.4.17.6
alanine carboxypeptidase
3.5.1.13
aryl-acylamidase
|
–
–
–
–
–
–
–
–
–
–
|
|
|
BRENDA:
BS140304
|
|
|
|
FVNQHLCGSHLVEALYLVCGERGFFYTPKA + H2O <=> FVNQHLCGSHL + VEA + L-leucine + L-tyrosine + LVCGERGF + L-phenylalanine + YTPKA
|
3.4.23.2
pepsin B
|
–
|
|
|
BRENDA:
BS384736
|
|
|
|
Leu-Phe + H2O <=> L-leucine + L-phenylalanine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.16
Xaa-Trp aminopeptidase
3.4.11.17
tryptophanyl aminopeptidase
3.4.11.22
aminopeptidase I
3.4.11.23
PepB aminopeptidase
3.4.13.18
cytosol nonspecific dipeptidase
3.4.13.19
membrane dipeptidase
3.5.1.13
aryl-acylamidase
|
–
–
–
–
–
–
–
–
–
|
|
|
BRENDA:
BS140302
|
|
|
|
Phe-Leu + H2O <=> L-phenylalanine + L-leucine
|
3.4.11.1
leucyl aminopeptidase
3.4.11.17
tryptophanyl aminopeptidase
3.4.11.22
aminopeptidase I
3.4.11.23
PepB aminopeptidase
3.4.13.18
cytosol nonspecific dipeptidase
|
–
–
–
–
–
|
|
|
BRENDA:
BS364786
|
|
|
|
L-phenylalanine + L-leucine <=> glycine + glycine + glycine
|
3.1.1.7
acetylcholinesterase
|
–
|
|
|
BRENDA:
BS83084
|
|
|
|
L-phenylalanine + 4-methyl-2-oxopentanoate <=> phenylpyruvate + L-leucine
|
2.6.1.28
tryptophan---phenylpyruvate transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.51
serine---pyruvate transaminase
2.6.1.64
glutamine---phenylpyruvate transaminase
|
–
–
–
–
|
|
|
BRENDA:
BS356447
|
|
|
|
beta-Ala-L-Leu + H2O <=> beta-Alanine + L-leucine
|
3.4.13.20
beta-Ala-His dipeptidase
|
–
|
|
|
BRENDA:
BS411737
|
|
|
|
L-leucine + H2O + Leu-Phe <=> L-phenylalanine
|
3.4.11.2
membrane alanyl aminopeptidase
|
–
|
|
|
SABIO-RK:
9734
|
|
|
|
N-Succinyl-L-Leu + H2O <=> succinate + L-leucine
|
not assigned
|
–
|
|
|
SABIO-RK:
9751
|
|